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Some new science on gene editing…..

Summary from AI;

Most rare diseases aren’t “rare” in aggregate — 400 million people worldwide have one.
But each specific mutation is rare, so big pharma won’t touch them because the economics are hopeless.

Liu’s new approach (PERT) is a mutation-agnostic gene-editing engine for diseases caused by prematur…[Read more]

Personally, I disagree somewhat with the heading that “Groupthink in science isn’t a problem; it’s a myth.”

In principle, yes. In practice, Groupthink happens whenever careers, funding, prestige, or consensus incentives push people to ‘not rock the boat’. Science has mechanisms to counter this, but those mechanisms are imperfect.…[Read more]

This is going to be a hugely successful album. Millions of plays already on Spotify. Not my usual scene but the musicianship is top class.

https://en.wikipedia.org/wiki/Lux_(Rosal%C3%ADa_album)

There’s no evidence that a cartel vs government conflict is directly causing measles vaccine supply problems in Mexico. But cartel control of territory does indirectly make healthcare delivery harder in some regions. So the relationship is indirect and structural, not the main driver. Public-health workers sometimes avoid cartel-dominated areas. T…[Read more]

Did I not answer your questions? Oh, I didn’t! I would call them secondary to the main questions about R nought, the anti-vax movement, and flaws or laziness in human cognition.

@PopeBeanie – Yes, you are correct with the basics of ‘R Nought (12-18). But it does not explain why Canada lost elimination status before the US. But elimination statu…[Read more]

..or at least a non sequitur….as most people who use the Galileo Gambit aren’t making a formal logical argument….it appeals not to reason but to ego, making it less an argument and more a psychological defense mechanism.

Yes, I guess it is more of a cognitive bias than a logical fallacy.

Cheers Strega! Hope all is good with you!

I am still thinking about what the ideas of the Enlightenment……..

The Lillian Hellman Fallacy and the Galileo Gambit.

There’s a predictable pattern in modern argument, especially online, where someone with a weak or poorly supported claim begins by presenting themselves as a courageous dissenter—someone who “refuses to cut their consc…[Read more]

Thanks Reg!!

Have a great week!

Appreciate it, PopeBeanie….I just rhyme what the evidence taught.
Gift of the gab, not the gift of God……
Critical thinking’s my creed, skepticism my sport.

Once you no longer reserve a hidden compartment in your reasoning for “maybe there’s a divine exception,” the entire field of view opens up. You stop having to protect contradictions, and patterns that were once blurred by reverence or taboo become visible. I don’t carry a residual conceptual veto. When you remove that invisible constraint of ma…[Read more]

Thanks, Reg!

Have a great week!

Thanks Jake, I was mostly thinking about Ireland when I wrote that :-).

The Enlightenment was about freeing thought from authority, be that authority religious, royal, or dogmatic. Now the new authorities are hashtags and outrage algorithms. The problem is not just ideological, it’s epistemic. Both the ‘Lunatic Left and Rancid Right’ have abandoned Enlightenment principles like reason, evidence, and open debate in fa…[Read more]